What do we (not) know about how paracetamol (acetaminophen) works?

Do We Know What We Do not Know? A Response to Celine Bonnet

Diagnostic and therapeutic challenges for dermatologists: What shall we do when we don’t know what to do?

What shall we do when we have done everything we could for the diagnosis and treatment of a patient, but were not successful? What shall we do when there is no definite treatment for a patient? What shall we do when we have no diagnosis or treatment for a patient? Some useful suggestions are presented here to get rid of these situations.

Perioperative Analgesic Pharmacology in Children

1. Name the 4 main classes of analgesic drugs. 2. How does paracetamol work? 3. By what routes may paracetamol be given? 4. What is the oral loading dose of paracetamol? 5. Paracetamol may be used to treat: a. mild pain? b. moderate pain? c. severe pain? 6. How do NSAID’s work 7. In what situations should you be cautious about using NSAID’s? 8. By what routes may NSAID’s be given? 9. Is morphin...

Welcome to virosphere

Viruses may seem alien, but they are the most abundant and, arguably, the most important organisms on Earth. They are found just about everywhere, from oceans and forests to the people around you and, of course, in and on you as well. This world of strange, quasi-living things has been dubbed the virosphere, and it is a mysterious one – we know less about viruses than any other life form. But t...

Molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

Invasive aspergillosis (IA) are a major complication in immunocompromized patients where can be serious and rapidly fatal. Early diagnosis and early appropriate antifungal treatment is important in reducing mortality and morbidity. But despite many efforts to develop detection methods, the diagnosis of IA still remains challenging and current conventional methods are limited for adequate diagno...